This week’s Morphology Monday featured a 35-year-old patient presenting with anaemia, fatigue, and mild splenomegaly. The FBC showed:

• Hb: 102 g/L
• MCV: 59 fL
• MCH: 18 pg
• RDW: 24.6%

The blood film, stained with a supravital stain, revealed distinctive “golf ball” inclusions, blue precipitates within red cells. These represent HbH inclusion bodies, confirming the diagnosis of HbH disease, a form of alpha thalassaemia caused by deletion or inactivation of three alpha-globin genes.