Morphology Monday | Case MM260112
The blood film images are from a transfusion dependent patient who is a compound heterozygote for HbE/beta-thalassaemia.
The blood film images are from a transfusion dependent patient who is a compound heterozygote for HbE/beta-thalassaemia.
Don’t let a nucleolus default you to “Blast”: Always assess the chromatin density.
62 year old patient presented to ED. Her FBC showed an increased white cell population with the analyser unable to differentiate them properly. The BMS reported them as blasts. Was this correct?
A blood film was prepared for review, and the key morphological feature for participants to identify was a stomatocyte.
This week’s case comes from a 46 year old male who presented to his GP with no significant past medical history, does not take regular medications, and reports no recent infections. He drinks alcohol socially but not excessively.
These features are classical for CLL. The combination of a markedly elevated lymphocyte count, characteristic morphology, and a supporting clinical picture strongly points to chronic lymphocytic leukaemia as the final diagnosis.
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This week’s case comes from an 84-year-old male who was referred to the haematology team after routine blood tests showed a markedly raised white cell count. Clinically, he reported several weeks of general fatigue but no acute symptoms. He was otherwise well and presented via his GP.
This tool allows you to generate blood component barcodes on an image that can then be used for training, either scanning directly on the screen or by downloading the generated image.
These features are characteristic of May–Hegglin anomaly, one of the MYH9-related disorders. This group of rare inherited conditions presents with thrombocytopenia and large platelets, sometimes accompanied by hearing loss, renal abnormalities, or cataracts.