MM250609: Chronic myeloid leukaemia (CML)
CML is a myeloproliferative neoplasm driven by the BCR:ABL1 fusion gene
Morphology Monday | Case MM250609
Case from an 80 something year old male who arrived with fatigue, early satiety, and notable weight loss.
MM250602: Platelet Satellitism
This week’s Morphology Monday case featured a fascinating artefact, platelet satellitism, where platelets appear to “cluster” around white blood cells, particularly neutrophils though it has also been reported around other white cells as well. Platelet satellitism is an in vitro phenomenon in which platelets surround and stick to neutrophils in a rosette-like fashion on a…
Is morphology dead? Why blood films still matter in the age of automation
I explore where automation falls short and why human interpretation remains essential in spotting artefacts, reactive changes, and complex cell morphologies.
Infectious mononucleosis: when lymphocytes take centre stage
Infectious mononucleosis (IM), also known as glandular fever, is a common clinical presentation in adolescents and young adults, often caused by the Epstein-Barr virus (EBV).
Red Cells: Howell-Jolly bodies
Howell-Jolly bodies are small, round inclusions
Haemoglobinopathies – The small details that make a big difference Webinar
Only Cells hosted another successful Webinar titled “Haemoglobinopathies – the small details that make a big difference”.
Sickled crescents (short poem)
Red cells twist in crescent shape…
Wavy wonders: Borrelia’s appearance under the microscope
Borrelia’s morphology is distinct; they appear as thin, helical (spiral-shaped) organisms
Increased adhesion of blast cells in acute myeloid leukaemia
A notable feature of AML is the increased adhesiveness of these blast cells, leading them to adhere more firmly to each other and to the bone marrow microenvironment.