MM250714: Thalassaemia
These findings raised the possibility of a haemoglobinopathy. Given the red cell morphology and raised RDW, follow-up testing was advised.
These findings raised the possibility of a haemoglobinopathy. Given the red cell morphology and raised RDW, follow-up testing was advised.
This week’s Morphology Monday features a 60-year-old female with a history of chronic anaemia and persistent fatigue. Her most recent full blood count was performed as part of ongoing investigation and follow-up.
The findings pointed toward a diagnosis of megaloblastic anaemia, in this case most likely due to vitamin B12 deficiency.
Patient went to their GP and presented with fatigue and shortness of breath.
Howell-Jolly bodies are small, round inclusions
Red cells twist in crescent shape…
HUS is a form of MAHA
Drepanocytes or as they are commonly known, sickle cells…
Acanthocytes are red blood cells with irregular, spiky protrusions (spicules) on their surface.
Refers to pale red cells