This week’s Morphology Monday comes from a 6 year old child who has been experiencing chronic anaemia with intermittent jaundice. The child’s parents reported episodes of fatigue, irritability, and poor growth compared to siblings. There’s also a history of neonatal jaundice requiring phototherapy.

The child presented with pallor and mild scleral icterus. Splenomegaly was noted on examination.

Laboratory findings:

• Hb: 78 g/L
• MCV: 55 fL
• MCHC: 365 g/L
• Reticulocytes: 9%
• Total Bilirubin: Elevated (predominantly indirect)
• LDH: Raised
• Direct Antiglobulin Test (DAT): Negative

What do you think it could be? Stay tuned for the end of the week summary!