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15 Sept 2025#morphology-monday#only-cells#red-cells

Morphology Monday | Case MM250915

This week’s case comes from a 35-year-old patient who presented with:

  • Fatigue and mild shortness of breath

  • A history of intermittent anaemia

  • Mild splenomegaly on examination

The laboratory results showed:

  • WBC: 7.4 × 10⁹/L (normal)

  • RBC: 5.69 × 10¹²/L (slightly raised)

  • Hb: 102 g/L (low)

  • HCT: 0.335 (low)

  • MCV: 59 fL (low)

  • MCH: 18.0 pg (low)

  • RDW: 24.6 % (raised)

  • Platelets: 157 × 10⁹/L (normal)

Special investigations:

No evidence of common haemoglobin variants (HbS, HbC) or β-thalassaemia trait. The sample was referred for further molecular analysis.

The blood film images above are stained using a special stain. What is the stain used and what is the diagnosis?