Morphology Monday | Case MM251020
A middle aged traveller presented with mild, recurring fevers and general malaise several weeks and a slightly reduced platelet count. Blood films were made to assess the cause.
A middle aged traveller presented with mild, recurring fevers and general malaise several weeks and a slightly reduced platelet count. Blood films were made to assess the cause.
The case underlines how multiple comorbidities can converge to produce complex red cell morphology.
The blood film, stained with a supravital stain, revealed distinctive “golf ball” inclusions, blue precipitates within red cells.
This week’s case comes from a 35-year-old patient who presented with fatigue, mild shortness of breath and intermittent anaemia
This week’s case comes from a 29-year-old male who returned from a recent trip abroad. He presented to the emergency department with fever, chills, sweats, headache, and general malaise.
The blood film demonstrated striking red cell fragmentation with marked anisopoikilocytosis, microspherocytes, and budding cells, giving an appearance reminiscent of thermal burns – a hallmark of Hereditary Pyropoikilocytosis (HPP).
This week’s Morphology Monday comes from a 6 year old child who has been experiencing chronic anaemia with intermittent jaundice.
The blood film showed red cell fragmentation with schistocytes and occasional microspherocytes. ADAMTS13 activity was normal, helping to exclude thrombotic thrombocytopaenic purpura (TTP).
This week’s case comes from a 35-year-old male who presented with fatigue and pallor, easy bruising, and reduced urine output.
This week’s Morphology Monday case features a patient with known Sickle Cell Disease (SCD)