MM250818: Haemolytic uraemic syndrome (HUS)
The blood film showed red cell fragmentation with schistocytes and occasional microspherocytes. ADAMTS13 activity was normal, helping to exclude thrombotic thrombocytopaenic purpura (TTP).
Morphology Monday | Case MM250818
This week’s case comes from a 35-year-old male who presented with fatigue and pallor, easy bruising, and reduced urine output.
MM250728: Sickle cell disease
This week’s Morphology Monday case features a patient with known Sickle Cell Disease (SCD)
Morphology Monday | Case MM250728
This week’s Morphology Monday case comes from a 26-year-old individual with a known history of anaemia who presented to A&E with generalised fatigue, mild jaundice, and bone pain in the lower limbs.
MM250714: Thalassaemia
These findings raised the possibility of a haemoglobinopathy. Given the red cell morphology and raised RDW, follow-up testing was advised.
Morphology Monday | Case MM250714
This week’s Morphology Monday features a 60-year-old female with a history of chronic anaemia and persistent fatigue. Her most recent full blood count was performed as part of ongoing investigation and follow-up.
MM250630: Megaloblastic Anaemia
The findings pointed toward a diagnosis of megaloblastic anaemia, in this case most likely due to vitamin B12 deficiency.
Red Cells: Howell-Jolly bodies
Howell-Jolly bodies are small, round inclusions
Sickled crescents (short poem)
Red cells twist in crescent shape…
Haemolytic uraemic syndrome (HUS)
HUS is a form of MAHA