Morphology Monday | Case MM251103
This week we have a case from a 61-year-old patient who presented with persistent fatigue and unintentional weight loss. Routine bloods were performed, and the full blood count has raised some important red flags.
MM251027: Acute myeloid leukaemia
The blood film showed numerous myeloid blasts with Auer rods, supporting the diagnosis of AML. Flow cytometry revealed a blast population accounting for 88.7% of total cells, with a myeloid immunophenotype
Morphology Monday | Case MM251027
This week’s case comes from a 59-year-old male who presented to the Emergency Department with fatigue, shortness of breath, and spontaneous bruising that had developed over several weeks.
MM251013: Acute promyelocytic leukaemia (APML)
The blood film shows a genuine thrombocytopaenia, with a leukocytosis comprising predominantly of promyelocytes with Auer rods. The cells have immature nucleoli, abundant cytoplasmic granulation and approximately 25%% of the cells are bilobed. These are consistent with acute promyelocytic leukaemia.
Morphology Monday | Case MM251013
This week’s Morphology Monday case is from a 57 year old who presented to the emergency department.
MM251006: Lymphoproliferative disorder (?PLL)
The findings are in keeping with a lymphoproliferative disorder (LPD). Given the predominance of prolymphocytes, the picture is suggestive of Prolymphocytic Leukaemia (PLL). However, this would require confirmation by flow cytometry to establish lineage and clonality.
Morphology Monday | Case MM251006
This week’s case comes from a 62-year-old female whose sample was flagged by the analyser, but interestingly, no differential count was produced. The WBC scattergram showed an abnormal grey plot, prompting a manual film review.
MM250804: Multiple myeloma
This week’s case explored a blood film from a patient with known multiple myeloma, now presenting with progressive symptoms and worsening cytopenias.
Morphology Monday | Case MM250804
This week’s case comes from a 69 year old male presenting with a increasing fatigue and back back over the past several months. He has also experiences recurrent infections recently.
Morphology Monday | Case MM250721
This week’s case features a 14-year-old male who had just celebrated his birthday when he presented to hospital with an abnormal full blood count and some concerning symptoms.