Morphology Monday | Case MM250908
This week’s case comes from a 29-year-old male who returned from a recent trip abroad. He presented to the emergency department with fever, chills, sweats, headache, and general malaise.
This week’s case comes from a 29-year-old male who returned from a recent trip abroad. He presented to the emergency department with fever, chills, sweats, headache, and general malaise.
The blood film demonstrated striking red cell fragmentation with marked anisopoikilocytosis, microspherocytes, and budding cells, giving an appearance reminiscent of thermal burns – a hallmark of Hereditary Pyropoikilocytosis (HPP).
This week’s Morphology Monday comes from a 6 year old child who has been experiencing chronic anaemia with intermittent jaundice.
The blood film showed red cell fragmentation with schistocytes and occasional microspherocytes. ADAMTS13 activity was normal, helping to exclude thrombotic thrombocytopaenic purpura (TTP).
This week’s case comes from a 35-year-old male who presented with fatigue and pallor, easy bruising, and reduced urine output.
This week’s Morphology Monday case features a patient with known Sickle Cell Disease (SCD)
This week’s Morphology Monday case comes from a 26-year-old individual with a known history of anaemia who presented to A&E with generalised fatigue, mild jaundice, and bone pain in the lower limbs.
These findings raised the possibility of a haemoglobinopathy. Given the red cell morphology and raised RDW, follow-up testing was advised.
This week’s Morphology Monday features a 60-year-old female with a history of chronic anaemia and persistent fatigue. Her most recent full blood count was performed as part of ongoing investigation and follow-up.
The findings pointed toward a diagnosis of megaloblastic anaemia, in this case most likely due to vitamin B12 deficiency.