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30 Jun 2025#morphology-monday

Morphology Monday | Case MM250630

This week's Morphology Monday case is from a patient who went to their GP and presented with fatigue and shortness of breath. A full blood count was requested as part of the initial workup.

FBC results:

  • WBC: 7.60 ×10⁹/L

  • RBC: 1.44 ×10¹²/L

  • Hb: 60 g/L

  • MCV: 121.5 fL

  • MCH: 41.7 pg

  • Platelets: 240 ×10⁹/L

Additional lab results:

  • Vitamin B12: 90 ng/L (Low; reference range: 180–914 ng/L)

  • Serum Folate: 7.4 µg/L (Normal; reference range: 4.6–18.7 µg/L)

  • LDH: 1140 IU/L (Elevated; reference range: 125–220 IU/L)

Given the red cell indices and the biochemistry profile, what are your differentials?