MM250707: Splenic marginal zone lymphoma (SMZL)
This week’s case featured a patient with Splenic Marginal Zone Lymphoma (SMZL) a rare, indolent B-cell lymphoma typically involving the spleen, bone marrow, and peripheral blood
This week’s case featured a patient with Splenic Marginal Zone Lymphoma (SMZL) a rare, indolent B-cell lymphoma typically involving the spleen, bone marrow, and peripheral blood
…a patient who presented with fatigue and splenomegaly on examination. Routine bloods showed a significant lymphocytosis, prompting further investigation.
The findings are strongly suggestive of acute leukaemia of myeloid origin, though further flow cytometry and molecular testing are essential for classification.
a patient who presented with a gastrointestinal (GI) bleed and was started on tranexamic acid (TXA) as part of their management.
Images from a patient with APML.
Smear cells aren’t confirmatory for CLL.