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29 Sept 2025#morphology-monday#only-cells

Morphology Monday | Case MM250929

This week’s case comes from a patient with a complex clinical background. The patient presented with anaemia and a raised platelet count, alongside signs of systemic illness. Blood results included:

  • Hb: 106 g/L

  • MCV: 83.7 fL

  • MCH: 25.4 pg

  • Platelets: 740 ×10⁹/L

  • WBC: 25.4 ×10⁹/L

The blood film reveals some striking images.

Blood film from this case with many irregularly shaped red cells bearing spiky projections, and numerous platelets

Blood film from this case showing red cells with spiky, uneven projections and plentiful platelets

Blood film from this case with spiculated and irregular red cells, oval cells and platelets

Blood film from this case with spiky red cells, a few small dense cells and large platelets

Blood film from this case showing many red cells with irregular spiky projections among platelets

Blood film from this case with spiculated red cells and scattered platelets

What significant features can you see on the blood film images, and what do you think it could be?

As always, the summary of the case will be shared at the end of the week! Feel free to follow along with the case on LinkedIn at the Only Cells page or on the Only Cells Twitter page.