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1 Dec 2025#morphology-monday#only-cells#red-cells

Morphology Monday | Case MM251201

It's not often the first day of the month aligns with a Monday and you know what that means! It's time for a new case.

This week's case comes from a 46 year old male who presented to his GP with a few weeks of:

  • Increasing tiredness

  • Mild shortness of breath on exertion

  • Occasional light-headedness

He has no significant past medical history, does not take regular medications, and reports no recent infections. He drinks alcohol socially but not excessively. On examination:

  • Mild pallor noted

  • No jaundice

  • No hepatosplenomegaly

  • Vitals within normal limits

His GP requested routine blood tests, which showed some notable abnormalities and prompted the laboratory to review the blood film.

FBC Results showed:

  • Haemoglobin: 104 g/L

  • RBC: 3.5 × 10¹²/L

  • HCT: 0.32

  • MCV: 91 fL

  • MCH: 29.7 pg

  • MCHC: 326 g/L

  • RDW: 14.2%

  • WBC: 6.7 × 10⁹/L

  • Platelets: 480 × 10⁹/L

A blood film was prepared for morphology review:

What is the highlighted cell you can see in the image? What conditions do you associate with it?