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2 Feb 2026#morphology-monday#neutrophils#only-cells#red-cells#white-cells

Morphology Monday | Case MM260202

This week’s case features a patient currently in the Intensive Care Unit (ICU) suffering from acute liver failure. The laboratory data and the resulting blood film provide a sobering look at the systemic impact of hepatic collapse.

The clinical context:

The patient's FBC reveals a somewhat complex picture:

  • Hb: 67 g/L

  • PLT: 41 x 109/L

  • WBC: 8.1 x 109/L

While reviewing the blood film, the biomedical scientist noticed abnormalities in the red cells, but also interestingly some inclusions with the neutrophils.

The challenge:

  • What are the inclusions within the neutrophils called? They are sometimes referred to by a particularly ominous nickname.

  • In the context of liver failure, what does the presence of these inclusions signify for the patient's prognosis?

  • Aside from the neutrophil findings, what red cell features can you see on the film?

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