MM250728: Sickle cell disease
This week’s Morphology Monday case features a patient with known Sickle Cell Disease (SCD)
This week’s Morphology Monday case features a patient with known Sickle Cell Disease (SCD)
This week’s Morphology Monday case comes from a 26-year-old individual with a known history of anaemia who presented to A&E with generalised fatigue, mild jaundice, and bone pain in the lower limbs.
These findings raised the possibility of a haemoglobinopathy. Given the red cell morphology and raised RDW, follow-up testing was advised.
This week’s Morphology Monday features a 60-year-old female with a history of chronic anaemia and persistent fatigue. Her most recent full blood count was performed as part of ongoing investigation and follow-up.
The findings pointed toward a diagnosis of megaloblastic anaemia, in this case most likely due to vitamin B12 deficiency.
Patient went to their GP and presented with fatigue and shortness of breath.
Howell-Jolly bodies are small, round inclusions
Red cells twist in crescent shape…
HUS is a form of MAHA
Drepanocytes or as they are commonly known, sickle cells…