Earlier in the week a couple of blood film images were shared as part of this week’s Morphology Monday case. On closer inspection the blood film revealed both trophozoites and schizonts of Plasmodium malariae.
A middle aged traveller presented with mild, recurring fevers and general malaise several weeks and a slightly reduced platelet count. Blood films were made to assess the cause.
The case underlines how multiple comorbidities can converge to produce complex red cell morphology.
This week’s case comes from a patient with a complex clinical background. The patient presented with anaemia and a raised platelet count, alongside signs of systemic illness.
The blood film, stained with a supravital stain, revealed distinctive “golf ball” inclusions, blue precipitates within red cells.
This week’s case comes from a 35-year-old patient who presented with fatigue, mild shortness of breath and intermittent anaemia
This week’s case comes from a 29-year-old male who returned from a recent trip abroad. He presented to the emergency department with fever, chills, sweats, headache, and general malaise.
The blood film demonstrated striking red cell fragmentation with marked anisopoikilocytosis, microspherocytes, and budding cells, giving an appearance reminiscent of thermal burns – a hallmark of Hereditary Pyropoikilocytosis (HPP).
This week’s Morphology Monday comes from a 6 year old child who has been experiencing chronic anaemia with intermittent jaundice.
The blood film showed red cell fragmentation with schistocytes and occasional microspherocytes. ADAMTS13 activity was normal, helping to exclude thrombotic thrombocytopaenic purpura (TTP).
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